Shim-pack GISS series maintains the same ultra-high inertness and wider pH range as the Shim-pack GIST series while providing rapid separations with symmetric peaks.
Nexera XS inert - Options
Ultra High Performance Liquid Chromatograph
Quickest Way to Results
Improving the Efficiency of Process Steps in Analytical Method Development
LabSolutions™ MD
When evaluating manufacturing processes or testing the stability of pharmaceuticals, separating principal components and impurities in chromatograms is very important for characterization analysis and quality control, but establishing the appropriate separation parameters requires a significant amount of time and effort. LabSolutions MD enables efficient development of analysis methods using an Analytical Quality by Design (AQbD) approach based on scientific evidence and risk. All steps involved in the screening, optimization, and validation phases of the method development process can be completed using LabSolutions MD, from analyzing samples by automatically switching between respective mobile phases and columns to using the analytical results to build a design space, deciding the optimal analytical condition settings, and then evaluating robustness (validation).
Improves Efficiency of High-Sensitivity Analysis and Characterization of Oligonucleic Acid
LabSolutions Insight™ Biologics
LabSolutions Insight Biologics is a dedicated software platform for oligonucleotide characterization using the LCMS-9030 or LCMS-9050 quadrupole time-of-flight type (Q-TOF) mass spectrometer. Main product and impurity identification includes several core editors for sequence, nucleotides, linkers, ribose and base modifications. Together with processing and integration for target modifications, Insight Biologics is a comprehensive workspace for data review, processing, and reporting. Because the Nexera XS inert system prevents the adsorption of target components to metal surfaces, combining it with LabSolutions Insight Biologics creates an ideal setup for oligonucleotide characterization.
Unique Functionality Reduces Data Analysis Work
i-PeakFinder™
The process of identifying peaks obscured by baseline undulations or noise, identifying shoulder peaks with inadequate separation, and so on, can be very tedious and produce results that vary depending on skill level. Shimadzu's unique i-PeakFinder peak integration algorithm is perfect for accurately detecting peaks in troublesome chromatograms.
LC Columns
LC-MS Software
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LabSolutions Insight Biologics is software for analyzing the characteristics of oligonucleotides using the LCMS-9030 or LCMS-9050 quadrupole time-of-flight type (Q-TOF) mass spectrometer.
Related information
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The Nexera series is a family of HPLC systems that marries AI and IoT enhancements to set new industry standards. -
LabSolutions Insight Biologics is software for analyzing the characteristics of oligonucleotides using the LCMS-9030 or LCMS-9050 quadrupole time-of-flight type (Q-TOF) mass spectrometer.
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Excellent stability and performance could be achieved under a wide range of LC conditions with Shim-pack Scepter LC columns, which are the next generation organic silica hybrid based columns. -
Shim-pack Bio IEX Columns are available in Q (quaternary ammonium) and SP (sulfopropyl) chemistries and are based... -
With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates. -
Even for LC columns that claim to be designed for basic compounds, adequate resolution often can not be obtained due to problems such as leading of highly polar basic compounds, peak shape deterioration of acidic compounds, or long equilibration time required for low ionic strength acidic mobile phase.