MALDI-Based Instruments Comparison

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MALDI-Based Instruments Comparison

This page provides a quick overview of 7 models of MALDI-Based Instruments. Choose the model that best suits your analysis needs from the compact digital ion trap MS for on-the-spot analysis, the benchtop MALDI-TOF MS for routine analysis to the research grade MALDI TOF/TOF MS for a diverse range of applications.

Summary of Product Features
Comparison Table
Principle of MALDI-TOFMS

1. Summary of Product Features

MALDImini-1
MALDI digital ion trap mass spectrometer

“Minimum” footprint
With its simple configuration and compact size, it is possible to install the MALDImini-1 in places where mass
analysis devices could not previously be used.

“Minimum” time
Miniaturization allows rapid, "on-the-spot" analysis and simplifies data acquisition.

“Minimum” sample volume
Complex structural analysis can be performed even with sub-µL sample volumes.

MALDI-8030
Dual-polarity benchtop linear MALDI-TOF MS

Best-in-class sensitivity and resolution
Easily detect analytes for your application

Quickest to your result
Fast (200 Hz) solid-state laser and fast sample instruction using load-lock chamber

Small footprint/benchtop design
The smallest instrument in its class – saves your valuable laboratory space

Solutions for all your applications
Food & cosmetics, teaching & research labs, regulatory & manufacturing Labs

MALDI-7090
MALDI-TOF MS

High throughput and high resolution
True 2kHz acquisition speed in MS and MS/MS modes and high MS/MS resolution (10,000) via ASDF

Hyper-MS2, a new benchmark in MS/MS acquisition
Combining core technologies patented and exclusive to Shimadzu

Ultimate applications performance
Flexibly accommodate a wide range of analysis needs

AXIMA Performance
MALDI TOF/TOF mass spectrometer

Highly flexible research-grade MALDI TOF/TOF mass spectrometer
From high energy MS/MS of proteomics and other biological and organic samples to uncompromised analysis of high mass intact proteins

High performance in a robust and flexible design
Uncompromised linear mode performance for high mass analysis

Application-centric solutions
Provides total support for protein identification, LC-MALDI and biomarker discovery

Specifications

	Benchtop Instruments			Floor Standing Instruments
	MALDImini-1	MALD-8020	MALD-8030	MALD-7090	AXIMA Assurance	AXIMA Confidence	AXIMA Performance
Measurement type	Digital Ion Trap	Linear-TOF	Linear-TOF	Linear/Reflectron-TOF Reflectron-TOF/TOF	Linear/Reflectron-TOF	Linear/Reflectron-TOF Reflectron-TOF/TOF	Linear/Reflectron-TOF Reflectron-TOF/TOF
Measured ion	Positive	Positive	Positive and Negative	Positive and Negative	Positive and Negative	Positive and Negative	Positive and Negative
Mass range (m/z)	650-70,000	1-500,000 （Linear mode）	1-500,000 （Linear mode）	1-500,000 （Linear mode） 1-70,000 (Reflectron mode)	1-500,000 （Linear mode）	1-500,000 （Linear mode） 1-80,000 (Reflectron mode)	1-500,000 （Linear mode） 1-80,000 (Reflectron mode)
MS/MS function	CID up to MS³	-	-	CID/PSD (Post Source Decay)	-	Post Source Decay (PSD)	CID
Mass Resolution	> 4,000	> 5,000	> 5,000	> 6,000 (Linear mode) > 25,000 (Reflectron mode) > 10,000 (MS/MS)	> 5,000	> 5,000 （Linear mode） > 15,000 (Reflectron mode)	> 5,000 （Linear mode） > 20,000 (Reflectron mode)
Mass accuracy	External : 200 ppm	Internal : 20 ppm External : 150 ppm	Internal : 20 ppm External : 150 ppm	Internal : 2 ppm (Refrectron mode) 20 ppm (Linear mode)	Internal : <30 ppm External: <200 ppm	Internal : 10 ppm (Refrectron mode) 30 ppm (Linear mode)	Internal : 5 ppm (Refrectron mode) 30 ppm (Linear mode)
Throughput	0.3, 0.6 spectrum/s (Depend on mass range and scan speed)	50, 100, 200Hz (Variable)	50, 100, 200Hz (Variable)	1 - 2,000 Hz (Variable)	1 - 50 Hz (Variable)	1 - 50 Hz (Variable)	1 - 50 Hz (Variable)
Dimensions/ Weight	W309 × D385 × H320 mm 25 kg	W600 × D745 × H1,055 mm 86 kg	W600 × D745 × H1,055 mm 92 kg	W2,834 × D1,276 × H1,182 mm 875 kg	W700 × D850 × H1,920 mm 330 kg	W700 × D850 × H1,920 mm 345 kg	W700 × D850 × H1,920 mm 375 kg
Type	Benchtop	Benchtop	Benchtop	Floor standing	Floor standing	Floor standing	Floor standing

Applications

	Benchtop Instruments			Floor Standing Instruments
	MALDImini-1	MALD-8020	MALD-8030	MALD-7090	AXIMA Assurance	AXIMA Confidence	AXIMA Performance
Peptide mass fingerprinting
Protein sequencing
Glycans/ Glycopeptides investicgation
Synthetic peptides and Proteins
Screening analysis
Cell culture
Food/ Cosmetics
Small molecules
QA/QC
Polymer analysis
Oligonucleotide/ Primer analysis
Biomarker discovery
Proteomics
High-energy MS/MS of proteomics and other biological /Organic samples
High-mass intact proteins
MS Imaging
High thoughput screening
	MALDmini-1	MALD-8020	MALD-8030	MALD-7090	AXIMA Assurance	AXIMA Confidence	AXIMA Performance

3. Principle of MADI-TOFMS

What is MALDI?

MALDI is the abbreviation for "Matrix Assisted Laser Desorption/Ionization."
The sample for MALDI is uniformly mixed in a large quantity of matrix…

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MALDI-Based Instruments Comparison