Nexera lite inert
High Performance Liquid Chromatograph
Inert High Performance Liquid Chromatograph (HPLC) System
The analysis of proteins such as antibody drugs requires careful operation because a high-salt mobile phase sometimes corrodes the system. In addition, the adsorption of proteins to metal surfaces often results in poor chromatographic performance.
Providing the same expandability and superior performance advantages of the Nexera series HPLC Systems, the Nexera lite inert is the ideal solution for addressing challenges related to metal-adsorption that compromise quantitative accuracy, sensitivity, or separation and mobile phases that cause system durability problems. It is a robust HPLC system that eliminates the risk of corrosion by high-salt mobile phases and sample adsorption onto metal surfaces with a maximum pressure tolerance of 20 MPa. It also improves the data quality of protein analysis in biological samples with superior reproducibility, without any special considerations for stable and long-term use.
Features
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Aggregates of antibody drugs show immunogenicity and cause a decrease in the purification efficiency and production. Therefore, an aggregation test is one of the most critical evaluations when manufacturing biopharmaceuticals and controlling their quality.
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Nexera lite inert provides good repeatability of retention time because the solvent delivery unit LC-40i of Nexera lite inert can deliver mobile phases accurately.
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The pH Monitor, pHM-40, continuously monitors and records the pH of the mobile phase. The pH and detector chromatograms are saved within the same data file and can be overlapped, ensuring efficient data traceability.
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