LCMS-2050

The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy to use high-level performance and compactness.

This video shows you how easy it is to change the Desolvation Line, or inlet capillary, on Shimadzu’s compact, high-performance single quad LCMS-2050 mass spectrometer.

Thanks to its size and ease of use, the LCMS-2050 can be used in the same way as an LC system, even by those unfamiliar with mass spectrometers. In this video, we will provide a concise and easy to understand description of the LCMS-2050.

This video presents Shimadzu's latest single quadrupole mass spectrometer, the LCMS-2050. The LCMS-2050 is a mass detector designed with chemists in mind. With the new Heated Dual Ion Source, Mass-it Technology, and Ultra-Fast Mass Spectrometry (UFMS) capabilities, LCMS-2050 offers deeper insights into the data without the complexity of a typical MS analysis.

This video demonstrated how easy it is to perform routine maintenance on Shimadzu new single quadrupole spectrometer- LCMS2050. Maintenance of LCMS is very important to ensure that the instrument is always in good condition and hence producing accurate results consistently. As such, it is important to ensure that users have equipped with the necessary knowledge and skill to perform basic maintenance. LCMS2050 is designed to be easy maintained by user themselves. Besides demonstrating the maintenance process including ESI capillary & DL pipe replacement, and cleaning of ion guide, this video also showcased the fast vacuum start up of LCMS2050 after maintenance.

Various LC-MS systems are used today, such as LC-MS single quadrupole system, LC-MS/MS triple quadrupole system and LC - quadrupole - time of flight, abbreviated as LC-Q-TOF system, and so on. This video introduces the features, advantages and applications in solving analytical problems of the different LC-MS systems. Taking sulfamerazine as an example, it explains from the ionization to mass spectra of the compound measured on the three types of LC-MS. LC-MS single quadrupole is used mainly for confirmation and quantitation in scan mode and/or SIM mode. LC-MS/MS triple quadruple can be operated in multiple modes such as Multiple Reaction Monitoring (MRM) and product ion scan etc. due to the QqQ configuration. It is particularly important in quantitation of trace level compounds by MRM mode method. While high resolution LC-Q-TOF provides the capability of measuring accurate masses of compounds in MS and MS/MS modes. The combination of accurate mass and MS/MS spectrum made it powerful in identification of unknown compounds and structural elucidation study. The latest models of LC-MS from Shimadzu are LCMS-2050, LCMS-8060NX and LCMS-9050, which have a common feature – ultrafast mass spectrometry or UFMS. This unique feature benefits greatly screening analysis for many targeted or un-targeted compounds such as pesticides, metabolites and toxicological compounds etc. with assistance of data analysis software.