Articles on Metabolomics

2019

Decomposition and oxidation of methionine and tryptophan following irradiation with a nonequilibrium plasma jet and applications for killing cancer cells
Giichiro Uchida, Yusuke Mino, Tensho Suzuki, Jun-ichiro Ikeda, Takashi Suzuki, Kosuke Takenaka, Yuichi Setsuhara
Scientific Reports (2019), 9, Article number: 6625. https://doi.org/10.1038/s41598-019-42959-4

Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids
Christopher J. Vavricka, Takanobu Yoshida, Yuki Kuriya, Shunsuke Takahashi, Teppei Ogawa, Fumie Ono, Kazuko Agari, Hiromasa Kiyota, Jianyong Li, Jun Ishii, Kenji Tsuge, Hiromichi Minami, Michihiro Araki, Tomohisa Hasunuma, Akihiko Kondo
Nature Communications (2019), 10, Article number: 2015. https://doi.org/10.1038/s41467-019-09610-2

LC-MS/MS Analysis of Bile Acids in In Vitro Samples
Debbie Dewaele, Pieter Annaert, Eef Hoeben
Experimental Cholestasis Research (2019). https://doi.org/10.1007/978-1-4939-9420-5

Effect of Rifampicin on the Plasma Concentrations of Bile Acid-O-Sulfates in Monkeys and Human Liver-Transplanted Chimeric Mice With or Without Bile Flow Diversion
Issey Takehara, Nobuaki Watanabe, Daiki Mori, Osamu Ando, Hiroyuki Kusuhara
Journal of Pharmaceutical Sciences (2019), 1-9. https://doi.org/10.1016/j.xphs.2019.03.021

Effect of the storage atmosphere on metabolomics of harvested tomatoes (Solanum lycopersicum L.)
Yuma Yokota, Takashi Akihiro, Surina Boerzhijin, Takeshi Yamada, Yoshio Makino
Food Science & Nutrition (2019), Volume 7, Issue 2. https://doi.org/10.1002/fsn3.923

High hydrostatic pressure pasteurization of a draft sake brewed using a Niigata-sake yeast
Kazuki Nomura, Minami Ikezaki, Chihiro Kataoka, Saori (Ujiie) Hori, Toshio Aoki, Takashi Kuribayashi, Mitsuoki Kaneoke, Akinori Iguchi, Toru Shigematsu
High Pressure Research (2019), Issue 2, 301-312. https://doi.org/10.1080/08957959.2019.1598985

A Method for Determination of One Hundred Endogenous Steroids in Human Serum by Gas Chromatography-Tandem Mass Spectrometry
M. HILL, V. HÁNA Jr., M. VELÍKOVÁ, A. PAŘÍZEK, L. KOLÁTOROVÁ, J. VÍTKŮ, T. ŠKODOVÁ, M. ŠIMKOVÁ, P. ŠIMJÁK, R. KANCHEVA, M. KOUCKÝ, Z. KOKRDOVÁ, K. ADAMCOVÁ, A. ČERNÝ, Z. HÁJEK, M. DUŠKOVÁ, J. BULANT, L. STÁRKA
PHYSIOLOGICAL RESEARCH (2019), 68: 179-207. https://doi.org/10.33549/physiolres.934124

Development and Validation of a LC–MS/MS-Based Assay for Quantification of Free and Total Omega 3 and 6 Fatty Acids from Human Plasma
Vlad Serafim, Diana-Andreea Tiugan, Nicoleta Andreescu, Alexandra Mihailescu, Corina Paul, Iulian Velea, Maria Puiu, Mihai Dinu Niculescu
Molecules (2019), 24(2), 360. https://doi.org/10.3390/molecules24020360

Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors
Peter L. Voyvodic, Amir Pandi, Mathilde Koch, Ismael Conejero, Emmanuel Valjent, Philippe Courtet, Eric Renard, Jean-Loup Faulon, Jerome Bonnet
Nature Communications (2019), 10, Article number: 1697. https://doi.org/10.1038/s41467-019-09722-9

Identification and characterization of forced degradation products and stability‐indicating assay for notoginsenosidefc by using UHPLC‐Q‐TOF‐MS and UHPLC‐MS/MS: Insights into stability profile and degradation pathways
Chao Ma, Huida Guan, Zhengcai Ju, Shuping Li, Gang Deng, Yunpeng Zhang, Qiyan Lin, Xuemei Cheng, Li Yang, Zhengtao Wang, Changhong Wang
JOURNAL OF SEPARATION SCIENCE (2019), 42 (8), 1477–1658. https://doi.org/10.1002/jssc.201801295

Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers
Hideaki Ogiwara, Kazuaki Takahashi, Mariko Sasaki, Takafumi Kuroda, Hiroshi Yoshida, Reiko Watanabe, Ami Maruyama, Hideki Makinoshima, Fumiko Chiwaki, Hiroki Sasaki, Tomoyasu Kato, Aikou Okamoto, Takashi Kohno
Cancer Cell (2018), Volume 35, Issue 2, 177-190. https://doi.org/10.1016/j.ccell.2018.12.009

Combination of cell metabolomics and pharmacology: A novel strategy to investigate the neuroprotective effect of Zhi-zi-chi decoction
Yin Zhang, Yuan Yao, Xiaolei Shi, Jun Fan, Taohong Huang, Jun Wen, Tingting Zhou
Journal of Ethnopharmacology (2019), Volume 236, 302-315. DOI: 10.1016/j.jep.2019.03.021

Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy
Junichi Sugawara, Daisuke Ochi, Riu Yamashita, Takafumi Yamauchi, Daisuke Saigusa, Maiko Wagata, Taku Obara, Mami Ishikuro, Yoshiki Tsunemoto, Yuki Harada, Tomoko Shibata, Takahiro Mimori, Junko Kawashima, Fumiki Katsuoka, Takako Igarashi-Takai, Soichi Ogishima, Hirohito Metoki, Hiroaki Hashizume, Nobuo Fuse, Naoko Minegishi, Seizo Koshiba, Osamu Tanabe, Shinichi Kuriyama, Kengo Kinoshita, Shigeo Kure, Nobuo Yaegashi, Masayuki Yamamoto, Satoshi Hiyama, Masao Nagasaki
BMJ Journals (2019), / Volume 9, Issue 2. http://dx.doi.org/10.1136/bmjopen-2018-025939

Characterization and Biodistribution Analysis of Oxygen-Doped Single-Walled Carbon Nanotubes Used as in Vivo Fluorescence Imaging Probes
Tsukasa Takeuch Yoko Iizum, Masako Yudasak, Shinae Kizaka-Kondoh, Toshiya Okazaki
Bioconjugate Chemistry (2019). DOI: 10.1021/acs.bioconjchem.9b00088

Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis
Hisyam Abdul Hamid, Akira Tanaka, Tomoaki Ida, Akira Nishimura, Tetsuro Matsunaga, Shigemoto Fujii, Masanobu Morita, Tomohiro Sawa, Jon M. Fukuto, Péter Nagy, Ryouhei Tsutsumi, Hozumi Motohashi, Hideshi Ihara, Takaaki Akaike
Redox Biology (2019), Volume 21, 101096. https://doi.org/10.1016/j.redox.2019.101096

Identification and Quantification by Targeted Metabolomics of Antibiotic-Responsive Urinary Small Phenolic Molecules Derived from the Intestinal Microbiota in Mice
Mark E. Obrenovich, George Eugene Jaskiw, Renliang Zhang, Belinda Willard, Curtis J. Donskey
Pathogens and Immunity (2019), Vol.4, No.1. DOI: 10.20411/pai.v4i1.284

Metabolomic approaches to polyamines including acetylated derivatives in lung tissue of mice with asthma
Hyeon-Seong Lee, Chan Seo, Yun-Ho Hwang, Tae Hwan Shin, Hyung-Jin Park, Youngbae Kim, Moongi Ji, Jeuk Min, Subin Choi, Hangun Kim, Ae Kyung Park, Sung-Tae Yee, Gwang Lee, Man-Jeong Paik
Metabolomics (2019), 15:8. https://doi.org/10.1007/s11306-018-1470-5

Age-Specific Cut-off Values of Amino Acids and Acylcarnitines for Diagnosis of Inborn Errors of Metabolism Using Liquid Chromatography Tandem Mass Spectrometry
Suprovath Kumar Sarker, Md Tarikul Islam, Aparna Biswas, Golam Sarower Bhuyan, Rosy Sultana, Nusrat Sultana, Shagoofa Rakhshanda, Mst. Noorjahan Begum, Asifuzzaman Rahat, Sharmina Yeasmin, Mowshori Khanam, Asim Kumar, Farjana Akther Noor, Abu A. Sajib, Abul B. M. M. K. Islam, Syeda Kashfi Qadri, Mohammod Shahidullah, Mohammad Abdul Mannan, A. K. M. Muraduzzaman, Tahmina Shirin, Sheikh Maksudur Rahman, Syed Saleheen Qadri, Narayan Saha, Sharif Akhteruzzaman, Firdausi Qadri, KaiissarMannoor
BioMed Research International (2019), Volume 2019, Article ID 3460902. https://doi.org/10.1155/2019/3460902

Leaf ER bodies identified in Arabidopsis rosette leaves are involved in defense against herbivory
Akiko Nakazaki, Kenji Yamada, Tadashi Kunieda, Ryosuke Sugiyama, Masami Yokota Hirai, Kentaro Tamura, Ikuko Hara-Nishimura, Tomoo Shimada
Plant Physiology (2019). https://doi.org/10.1104/pp.18.00984

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity
Takeshi Tanoue, Satoru Morita, Damian R. Plichta, Ashwin N. Skelly, Wataru Suda, Yuki Sugiura, Seiko Narushima, Hera Vlamakis, Iori Motoo, Kayoko Sugita, Atsushi Shiota, Kozue Takeshita, Keiko Yasuma-Mitobe, Dieter Riethmacher, Tsuneyasu Kaisho, Jason M. Norman, Daniel Mucida, Makoto Suematsu, Tomonori Yaguchi, Vanni Bucci, Takashi Inoue, Yutaka Kawakami, Bernat Olle, Bruce Roberts, Masahira Hattori, Ramnik J. Xavier, Koji Atarashi, Kenya Honda
Nature (2019), volume 565, 600–605. https://doi.org/10.1038/s41586-019-0878-z

Data on metabolic profiling of healthy human subjects' plasma before and after administration of the Japanese Kampo medicine maoto
Hiroyuki Kitagawa, Katsuya Ohbuchi, Masaya Munekage, Kazune Fujisawa, Yasuhiro Kawanishi, Tsutomu Namikawa, Hirotaka Kushida, Takashi Matsumoto, Chika Shimobori, Akinori Nishi, Chiharu Sadakane, Junko Watanabe, Masahiro Yamamoto, Kazuhiro Hanazaki
Data in Brief (2019), Volume 22, 359-364. https://doi.org/10.1016/j.dib.2018.11.116

Phenotyping analysis of the Japanese Kampo medicine maoto inhealthy human subjects using wide-targeted plasma metabolomics
Hiroyuki Kitagawa, Katsuya Ohbuchi, Masaya Munekage, Kazune Fujisawa, Yasuhiro Kawanishi, Tsutomu Namikawa, Hirotaka Kushida, Takashi Matsumoto, Chika Shimobori, Akinori Nishi, Chiharu Sadakane, Junko Watanabe, Masahiro Yamamoto, Kazuhiro Hanazaki
Journal of Pharmaceutical and Biomedical Analysis (2019), volume 164, 119–127

Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer
Takao Iemoto, Shin Nishiumi, Takashi Kobayashi, Seiji Fujigaki, Tetsuya Hamaguchi, Ken Kato, Hirokazu Shoji, Yasuhiro Matsumura, Kazufumi Honda, Masaru Yoshida
ONCOLOGY LETTERS (2019), 17: 831-842. https://doi.org/10.3892/ol.2018.9731

Interactive effects of osmotic stress and burrowing activity on protein metabolism and muscle capacity in the soft shell clam Mya arenaria
Fouzia Haider, Eugene P. Sokolov, Stefan Timm, Martin Hagemann, Esther Blanco Rayón, Ionan Marigómez, Urtzi Izagirre, Inna M. Sokolova
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology (2018), Volume 228, Pages 81-93. https://doi.org/10.1016/j.cbpa.2018.10.022

Functional screening of salt tolerance genes from a halophyte Sporobolus virginicus and transcriptomic and metabolomic analysis of salt tolerant plants expressing glycine-rich RNA-binding protein
Yuichi Tada, Ryuichi Kawano, Shiho Komatsubara, Hideki Nishimura, Maki Katsuhara, Soichi Ozaki, Shin Terashima, Kentaro Yano, Chisato Endo, Muneo Sato, Mami Okamoto, Yuji Sawada, Masami Yokota Hirai, Takamitsu Kurusu
Plant Science (2019), Volume 278, 54-63. https://doi.org/10.1016/j.plantsci.2018.10.019

Heat challenge influences serum metabolites concentrations and liver lipid metabolism in Japanese quail (Coturnix japonica)
Shaoxia PU, Kento USUDA, Kentaro NAGAOKA, Gen WATANABE
Journal of Veterinary Medical Science (2019), Vol. 81, No. 1, 77-83. https://doi.org/10.1292/jvms.18-0615

Simultaneous quantification of fifty-one odor-causing compounds in drinking water using gas chromatography-triple quadrupole tandem mass spectrometry
Chunmiao Wang, Jianwei Yu, Qingyuan Guo, Yu Zhao, Nan Cao, Zhiyong Yu, Min Yang
Journal of Environmental Sciences (2019). https://doi.org/10.1016/j.jes.2018.11.008

High-sensitive liquid chromatography-tandem mass spectrometry-based chiral metabolic profiling focusing on amino acids and related metabolites
Yosuke Nakano, Moyu Taniguchi, Eiichiro Fukusaki
Journal of Bioscience and Bioengineering (2019). https://doi.org/10.1016/j.jbiosc.2018.10.003

Metabolome analysis revealed the knockout of glyoxylate shunt as an effective strategy for improvement of 1-butanol production in transgenic Escherichia coli
Katsuaki Nitta, Walter A. Laviña, Sammy Pontrelli, James C. Liao, Sastia P. Putri, Eiichiro Fukusaki
Journal of Bioscience and Bioengineering (2019). https://doi.org/10.1016/j.jbiosc.2018.08.013

2018

A sterile hydroponic system for characterising root exudates from specific root types and whole‑root systems of large crop plants
Akitomo Kawasaki, Shoko Okada, Chunyan Zhang, Emmanuel Delhaize, Ulrike Mathesius, Alan E. Richardson, Michelle Watt, Matthew Gilliham, Peter R. Ryan
Plant Methods (2018) 14:114. https://doi.org/10.1186/s13007-018-0380-x

Nitrogen deprivation in Fusarium oxysporum promotes mycotoxin production via intermediates in the Krebs cycle and unreported methylmalonyl-CoA mutase activity
A. V. Karpe, M. S. Dunn, M. C. Taylor, T. Nguyen, C. Ong, T. Karla, S. Rockman, D. J. Beale
Metabolomics (2018), 14:160. https://doi.org/10.1007/s11306-018-1459-0

GCSH antisense regulation determines breast cancer cells' viability
Anna Adamus, Petra Müller, Bente Nissen, Annika Kasten, Stefan Timm, Hermann Bauwe, Guido Seitz, Nadja Engel
Scientific Reports (2018), volume 8, Article number: 15399. DOI:10.1038/s41598-018-33677-4

Free D-amino acids produced by commensal bacteria in the colonic lumen
Mitsuharu Matsumoto, Akihiro Kunisawa, Takanari Hattori, Shuichi Kawana, Yusuke Kitada, Hazuki Tamada, Shinichi Kawano, Yoshihiro Hayakawa, Junko Iida, Eiichiro Fukusaki
Scientific Reports (2018), volume 8, Article number: 17915. DOI:10.1038/s41598-018-36244-z

Rice Grain Quality Benchmarking Through Profiling of Volatiles and Metabolites in Grains Using Gas Chromatography Mass Spectrometry
Cindy Llorente, Rosario Jimenez, Jackie, Yariv Brotman, Alisdair R. Fernie, Nese Sreenivasulu
Rice Grain Quality (2018), 187-199. https://doi.org/10.1007/978-1-4939-8914-0_11

Metabolome analysis for pancreatic cancer risk in nested case-control study: Japan Public Health Center-based prospective Study
Takashi Nakagawa, Takashi Kobayashi, Shin Nishiumi, Akihisa Hidaka, Taiki Yamaji, Norie Sawada, Yuichi Hirata, Kodai Yamanaka, Takeshi Azuma, Atsushi Goto, Taichi Shimazu, Manami Inoue, Motoki Iwasaki, Masaru Yoshida, Shoichiro Tsugane
Cancer Science (2018), 109(5), 1672–1681. doi: 10.1111/cas.13573

Physiological Changes After Spa Treatment - a Focus on Endocrinology
M. BICIKOVA, L. MACOVA, L. KOLATOROVA, M. HILL, J. NOVOTNY, D. JANDOVA, L. STARKA
PHYSIOLOGICAL RESEARCH (2018), 67, 525-530.

May Circulating Steroids Reveal a Predisposition to Intrahepatic Cholestasis of Pregnancy in Non-Pregnant Women?
P. ŠIMJÁK, M. HILL, A. PAŘÍZEK, L. VÍTEK, M. VELÍKOVÁ, M. DUŠKOVÁ, R. KANCHEVA, J. BULANT, M. KOUCKÝ, Z. KOKRDOVÁ, K. ADAMCOVÁ, A. ČERNÝ, Z. HÁJEK, L. STÁRKA
PHYSIOLOGICAL RESEARCH (2018), 67, 499-510.

Angelica Stem: A Potential Low-Cost Source of Bioactive Phthalides and Phytosterols
Chengke Zhao, Yuan Jia, Fachuang Lu
Molecules (2018), 23(12). https://doi.org/10.3390/molecules23123065

Third DWF1 paralog in Solanaceae, sterol Δ24-isomerase, branches withanolide biosynthesis from the general phytosterol pathway
Eva Knoch, Satoko Sugawara, Tetsuya Mori, Christian Poulsen, Atsushi Fukushima, Jesper Harholt, Yoshinori Fujimoto, Naoyuki Umemoto, Kazuki Saito
PNAS (2018), 115 (34), 8096-8103. https://doi.org/10.1073/pnas.1807482115

Evidence for Chemopreventive and Resilience Activity of Licorice: Glycyrrhiza Glabra and G. Inflata Extracts Modulate Estrogen Metabolism in ACI Rats
Shuai Wang, Tareisha L. Dunlap, Lingyi Huang, Yang Liu, Charlotte Simmler, Daniel D. Lantvit, Jenna Crosby, Caitlin E. Howell, Huali Dong, Shao-Nong Chen, Guido F. Pauli, Richard B. van Breemen, Birgit M. Dietz, Judy L. Bolton
Cancer Prevention Research (2018), 11(12), 819-830. DOI:10.1158/1940-6207.CAPR-18-0178

Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo
Daisuke Ogasawara, Taka-Aki Ichu, Vincent F. Vartabedian, Jacqueline Benthuysen, Hui Jing, Alex Reed, Olesya A. Ulanovskaya, Jonathan J. Hulce, Amanda Roberts, Steven Brown, Hugh Rosen, John R. Teijaro, Benjamin F. Cravatt
Nature Chemical Biology (2018), volume 14, 1099–1108. https://doi.org/10.1038/s41589-018-0155-8

Rabbit plasma metabolomic analysis of Nitroproston^®: a multi target natural prostaglandin based-drug
Ksenia Shestakova, Alex Brito, Natalia V. Mesonzhnik, Natalia E. Moskaleva, Ksenia O. Kurynina, Natalia M. Grestskaya, Igor V. Serkov, Igor I. Lyubimov, Vladimir V. Bezuglov, Svetlana A. Appolonova
Metabolomics (2018) 14:112. https://doi.org/10.1007/s11306-018-1413-1

Reactive Persulfides from Salmonella Typhimurium Downregulate Autophagy-Mediated Innate Immunity in Macrophages by Inhibiting Electrophilic Signaling
Shahzada Khan, Shigemoto Fujii, Tetsuro Matsunaga, Akira Nishimura, Katsuhiko Ono, Tomoaki Ida, Khandaker Ahtesham Ahmed, Tatsuya Okamoto, Hiroyasu Tsutsuki, Tomohiro Sawa, Takaaki Akaike
Cell Chemical Biology (2018), Volume 25, Issue 11, 1403-1413. https://doi.org/10.1016/j.chembiol.2018.08.007
Tohoku University

Dietary Fiber Confers Protection against Flu by Shaping Ly6c^– Patrolling Monocyte Hematopoiesis and CD8⁺ T Cell Metabolism
Aurelien Trompette, Eva S. Gollwitzer, Celine Pattaroni, Isabel C. Lopez-Mejia, Erika Riva, Julie Pernot, Niki Ubags, Lluis Fajas, Laurent P. Nicod, Benjamin J. Marsland
Immunity (2018), Volume 48, Issue 5, 992-1005. https://doi.org/10.1016/j.immuni.2018.04.022

Metabolomics and network analysis reveal the potential metabolites and biological pathways involved in salinity tolerance of the halophyte Salvadora persica
Asha Kumari, Asish Kumar Parida
Environmental and Experimental Botany (2018), Volume 148, Pages 85-99. https://doi.org/10.1016/j.envexpbot.2017.12.021

NMR- and GC/MS-based metabolomic characterization of sunki, an unsalted fermented pickle of turnip leaves
Satoru Tomita, Toshihide Nakamura, Sanae Okada
Food Chemistry Volume (2018) 258, 30, Pages 25-34. https://doi.org/10.1016/j.foodchem.2018.03.038

Rapid synthesis of three-dimensional sulfur-doped porous graphene via solid-state microwave irradiation for protein removal in plasma sample pretreatment
Fan Li, Linyi Lu, Die Gao, Min Wang, Dandan Wang, Zhining Xia
Talanta (2018), Volume 185, 1, Pages 528-536. https://doi.org/10.1016/j.talanta.2018.04.027

Production of lipid mediators across different disease stages of dextran sulfate sodium-induced colitis in mice
Taiki Hamabata, Tatsuro Nakamura, Sakura Masuko, Shingo Maeda, Takahisa Murata
The Journal of Lipid Research (2018). doi: 10.1194/jlr.M079095

The impact of night-shift work on platelet function in healthy medical staff
Tomoko Nakao, Atsushi Yasumoto, Suzumi Tokuoka, Yoshihiro Kita, Takuya Kawahara, Masao Daimon, Yutaka Yatomi
Journal of Occupational Health (2018), Volume 60, 324-332. https://doi.org/10.1539/joh.2018-0027-FS

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State
Clair Crewe, Nolwenn Joffin, Joseph M. Rutkowski, Min Kim, Fang Zhang, Dwight A. Towler, Ruth Gordillo, Philipp E. Scherer
Cell (2018), Volume 175, ISSUE 3, 695-708. https://doi.org/10.1016/j.cell.2018.09.005

Orexigenic action of oral zinc: metabolomic analysis in the rat hypothalamus
Mika Nishiuchi, Kumiko Sakai, Hiroyuki Tajima, Kazuo Katayama, Fumiko Kimura, Seiko Hoshi, Tomoko Goto, Hitoshi Shirakawa, Michio Komai
Bioscience, Biotechnology, and Biochemistry (2018). http://www.tandfonline.com/loi/tbbb20

Sugar phosphate analysis with baseline separation and soft ionization by gas chromatography-negative chemical ionization-mass spectrometry improves flux estimation of bidirectional reactions in cancer cells
Nobuyuki Okahashi, Kousuke Maeda, Shuichi Kawana, Junko Iida, Hiroshi Shimizu, Fumio Matsuda
Metabolic Engineering (2018). https://doi.org/10.1016/j.ymben.2018.08.011

Hippocampal metabolism of amino acids by L-amino acid oxidase is involved in fear learning and memory
Kento Usuda, Takahiro Kawase, Yuko Shigeno, Susumu Fukuzawa, Kazuki Fujii, Haolin Zhang, Takamitsu Tsukahara, Shozo Tomonaga, Gen Watanabe, Wanzhu Jin, Kentaro Nagaoka
Scientific Reports (2018), volume 8

Identification of serum biomarkers of chemoradiosensitivity in esophageal cancer via the targeted metabolomics approach
Seiji Fujigaki, Shin Nishiumi, Takashi Kobayashi, Makoto Suzuki, Takao Iemoto, Takashi Kojima, Yoshinori Ito, Hiroyuki Daiko, Ken Kato, Hirokazu Shouji, Kazufumi Honda, Takeshi Azuma, Masaru Yoshida
Biomarkers in Medicine (2018). https://doi.org/10.2217/bmm-2017-0449

Effects of high ambient temperature on plasma metabolomic profiles in chicks
Shozo Tomonaga, Hirofumi Okuyama, Tetsuya Tachibana, Ryosuke Makino
Animal Science Journal (2018), Volume 89, Issue 2. https://doi.org/10.1111/asj.12951

Hippocampal metabolism of amino acids by L-amino acid oxidase is involved in fear learning and memory
Kento Usuda, Takahiro Kawase, Yuko Shigeno, Susumu Fukuzawa, Kazuki Fujii, Haolin Zhang, Takamitsu Tsukahara, Shozo Tomonaga, Gen Watanabe, Wanzhu Jin, Kentaro Nagaoka
Scientific Reports (2018), volume 8

Pre-clinical Pharmacokinetic and Metabolomic Analyses of Isorhapontigenin, a Dietary Resveratrol Derivative
Yu Dai1, Samuel C. M. Yeo, Peter J. Barnes, Louise E. Donnelly, Lai C. Loo, Hai-Shu Lin1
Front. Pharmacol. (2018), 11. https://doi.org/10.3389/fphar.2018.00753

Comparative analysis of metabolite changes in two contrasting rice genotypes in response to low-nitrogen stress
Xiuqin Zhao, Wensheng Wang, Ziyan Xie, Yongming Gao, Chunchao Wang, Muhammed Mahbubur Rashid, Mohammad Rafiqul Islam, Binying Fu, Zhikang Li
The Crop Journal. https://doi.org/10.1016/j.cj.2018.05.006

Comparative Targeted Proteomics of the Central Metabolism and Photosystems in SigE Mutant Strains of Synechocystis sp. PCC 6803
Yuma Tokumaru, Kiyoka Uebayashi, Masakazu Toyoshima, Takashi Osanai, Fumio Matsuda, Hiroshi Shimizu
Molecules (2018), 23(5), 1051. doi:10.3390/molecules23051051

The comprehensive characterization of adrenocortical steroidogenesis using two-dimensional ultra-performance liquid chromatography – electrospray ionization tandem mass spectrometry
Gellért Karvaly, Krisztián Kovács, Katalin Mészáros, Ibolya Kocsis, Attila Patócs, Barna Vásárhelyi
Journal of Pharmaceutical and Biomedical Analysis (2018), Volume 153, 10, Pages 274-283. https://doi.org/10.1016/j.jpba.2018.01.054

Metabolomics-based profiling of three terminal alkene-producing Jeotgalicoccus spp. during different growth phase
Filemon Jalu Nusantara Putra, Sastia Prama Putri, Eiichiro Fukusaki
Journal of Bioscience and Bioengineering (2018). https://doi.org/10.1016/j.jbiosc.2018.06.014

Gut Microbiota–Dependent Trimethylamine N-Oxide Predicts Risk of Cardiovascular Events in Patients With Stroke and Is Related to Proinflammatory Monocytes
Arash Haghikia, Xinmin S. Li, Thomas G. Liman, Nils Bledau, David Schmidt, Friederike Zimmermann, Nicolle Kränkel, Christian Widera, Kristina Sonnenschein, Aiden Haghikia, Karin Weissenborn, Daniela Fraccarollo, Markus M. Heimesaat, Johann Bauersachs, Zeneng Wang, Weifei Zhu, Udo Bavendiek, Stanley L. Hazen, Matthias Endres, Ulf Landmesser
Arterioscler Thromb Vasc Biol (2018) Vol 38, Issue 8. DOI: 10.1161/ATVBAHA.118.311023

Novel comprehensive multidimensional liquid chromatography approach for elucidation of the microbosphere of shikimate-producing Escherichia coli SP1.1/pKD15.071 strain
Francesco Cacciola, Domenica Mangraviti, Francesca Rigano, Paola Donato, Paola Dugo, Luigi MondelloEmail author, Hernan J. Cortes
Analytical and Bioanalytical Chemistry (2018), Volume 410, Issue 15, pp 3473–3482

Carotenoids and apocarotenoids determination in intact human blood samples by online supercritical fluid extraction-supercritical fluid chromatography-tandem mass spectrometry
Mariosimone Zoccali, Daniele Giuffrida, Fabio Salafia, Salvatore V. Giofrè, Luigi Mondello
Analytica Chimica Acta (2018). https://doi.org/10.1016/j.aca.2018.06.022

Bioactive Phenolics of the Genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS/MS Profile of the Siberian Species and Their Inhibitory Potential Against α-Amylase and α-Glucosidase
Daniil N. Olennikov, Nadezhda K. Chirikova, Nina I. Kashchenko, Vyacheslav M. Nikolaev, Sang-Woo Kim, Cecile Vennos
Front Pharmacol. (2018), 9: 756. doi: 10.3389/fphar.2018.00756

Determination of the metabolites of Δ9-tetrahydrocannabinol in urine and plasma using multiple reaction monitoring gas chromatography with triple quadrupole mass spectrometry
Allegra Leghissa, Zacariah L. Hildenbrand, Frank W. Foss Jr., Kevin A. Schug
SEPARATION SCIENCE PLUS (2018), Volume 1, Issue 1. https://doi.org/10.1002/sscp.201700006

Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
Sarah A. Best, David P. De Souza, Ariena Kersbergen, Antonia N. Policheni, Saravanan Dayalan, Dedreia Tull, Vivek Rathi, Daniel H. Gray, Matthew E. Ritchie, Malcolm J. McConville, Kate D. Sutherland
Cell Metabolism Volume 27, Issue 4, 3 (2018), 935-943. https://doi.org/10.1016/j.cmet.2018.02.006

Microbe participation in aroma production during soy sauce fermentation
Risa Harada, Masanobu Yuzuki, Kotaro Ito, Kazuki Shiga, Takeshi Bamba, Eiichiro Fukusaki
Journal of Bioscience and Bioengineering (2018). https://doi.org/10.1016/j.jbiosc.2017.12.004

Insights into the phylogenetic and molecular evolutionary histories of Fad and Elovl gene families in Actiniaria
Joachim M. Surm, Tarik M. Toledo, Peter J. Prentis, Ana Pavasovic
Ecology and Evolution (2018). https://doi.org/10.1002/ece3.4044

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P. Jedrychowski, Ana S. H. Costa, Maureen Higgins, Emily Hams, John Szpyt, Marah C. Runtsch, Martin S. King, Joanna F. McGouran, Roman Fischer, Benedikt M. Kessler, Anne F. McGettrick, Mark M. Hughes, Richard G. Carroll, Lee M. Booty, Elena V. Knatko, Paul J. Meakin, Michael L. J. Ashford, Louise K. Modis, Gino Brunori, Daniel C. Sévin, Padraic G. Fallon, Stuart T. Caldwell, Edmund R. S. Kunji, Edward T. Chouchani, Christian Frezza, Albena T. Dinkova-Kostova, Richard C. Hartley, Michael P. Murphy & Luke A. O'Neill
Nature (2018), volume 556, pages 113–117. doi:10.1038/nature25986

PII-like signaling protein SbtB links cAMP sensing with cyanobacterial inorganic carbon response
Khaled A. Selim, Florian Haase, Marcus D. Hartmann, Martin Hagemann, Karl Forchhammer
PNAS (2018), 201803790. https://doi.org/10.1073/pnas.1803790115

Quality assessment of cellular and tissue-based products using liquid chromatography-tandem mass spectrometry
Ayako Tominaga, Masato Sato, Takumi Takahashi, Eriko Toyoda, Kenichi Toyoda, Takashi Suzuki, Masatoshi Takahashi, Masahiko Watanabe, Ken Okazaki
Biochemical and Biophysical Research Communications (2018), Volume 496, Issue 2, 429-435. https://doi.org/10.1016/j.bbrc.2018.01.001 Get rights and content

Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis
Zhuzhen Zhang, Zhenzhen Zi, Eunice E. Lee, Jiawei Zhao, Diana C. Contreras, Andrew P. South, E. Dale Abel, Benjamin F. Chong, Travis Vandergriff, Gregory A. Hosler, Philipp E. Scherer, Marcel Mettlen, Jeffrey C. Rathmell, Ralph J. DeBerardinis & Richard C. Wang
Nature Medicine (2018). doi:10.1038/s41591-018-0003-0

Innovative methodology for the identification of soluble biomarkers in fresh tissues
Brunella Costanza, Andrei Turtoi, Akeila Bellahcène, Touko Hirano, Olivier Peulen, Arnaud Blomme, Vincent Hennequière, Eugene Mutijima, Jacques Boniver, Marie-Alice Meuwis, Claire Josse, Benjamin Koopmansch, Karin Segers, Takehiko Yokobori, Karim Fahmy, Marc Thiry, Carla Coimbra, Nancy Garbacki, Alain Colige, Dominique Baiwir, Vincent Bours, Edouard Louis, Olivier Detry, Philippe Delvenne, Masahiko Nishiyama, and Vincent Castronovo
Oncotarget (2018), 13; 9(12): 10665–10680. doi:10.18632/oncotarget.24366

Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases
Arnaud Blomme, Gaetan Van Simaeys, Gilles Doumont, Brunella Costanza, Justine Bellier, Yukihiro Otaka, Félicie Sherer, Pierre Lovinfosse, Sébastien Boutry, Ana Perez Palacios, Edwin De Pauw, Touko Hirano, Takehiko Yokobori, Roland Hustinx, Akeila Bellahcène, Philippe Delvenne, Olivier Detry, Serge Goldman, Masahiko Nishiyama, Vincent Castronovo & Andrei Turtoi
Oncogenevolume (2018), 37, 1237–1250. doi:10.1038/s41388-017-0018-x

Alterations in Docosahexaenoic Acid-Related Lipid Cascades in Inflammatory Bowel Disease Model Mice
Shin Nishiumi Email author, Yoshihiro Izumi, Masaru Yoshida
Digestive Diseases and Sciences (2018), 1–12. https://doi.org/10.1007/s10620-018-5025-4

Production of lipid mediators across different disease stages of dextran sodium sulfate-induced colitis in mice
Taiki Hamabata, Tatsuro Nakamura, Sakura Masuko, Shingo Maeda and Takahisa Murata
The Journal of Lipid Research (2018), 59, 586-595. doi: 10.1194/jlr.M079095

Untargeted profiling of Glycyrrhiza glabra extract with comprehensive two-dimensional liquid chromatography-mass spectrometry using multi-segmented shift gradients in the second dimension: Expanding the metabolic coverage
Yong Foo Wong, Francesco Cacciola, Soraya Fermas, Solange Riga, Darryl James, Valeria Manzin, Brice Bonnet, Philip John Marriott, Paola Dugo, Luigi Mondello
Electrophoresis (2018), 0, 1–8. https://doi.org/10.1002/elps.201700469

Development and application of a UHPLC–MS/MS metabolomics based comprehensive systemic and tissue-specific screening method for inflammatory, oxidative and nitrosative stress
Johannes C. Schoeman Email, Amy C. Harms, Michel van Weeghel, Ruud Berger, Rob J. Vreeken, Thomas Hankemeier
Analytical and Bioanalytical Chemistry (2018), Volume 410, Issue 10, 2551–2568. https://doi.org/10.1007/s00216-018-0912-2

Differences in metabolite profiles caused by pre-analytical blood processing procedures
Shin Nishiumi, Makoto Suzuki, Takashi Kobayashi, Masaru Yoshida
Journal of Bioscience and Bioengineering (2018), VOL. 125 No. 5, 613-618. https://doi.org/10.1016/j.jbiosc.2017.11.011

Tryptophan-kynurenine and lipid related metabolites as blood biomarkers for first-episode drug-naïve patients with major depressive disorder: An exploratory pilot case-control study
Nobuki Kuwano, Takahiro A. Kato, Daiki Setoyama, Mina Sato-Kasai, Norihiro Shimokawa, Kohei Hayakawa, Masahiro Ohgidani, Noriaki Sagata, Hiroaki Kubo, Junji Kishimoto, Dongchon Kang, Shigenob Kanba
Journal of Affective Disorders (2018), Volume 231, 15, Pages 74-82. https://doi.org/10.1016/j.jad.2018.01.014

Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry
Hisashi Johno, Kentaro Yoshimura Email author, Yuki Mori, Tokuhide Kimura, Manabu Niimi, Masaki Yamada, Tetsuo Tanigawa, Jianglin Fan, Sen Takeda
Metabolomics (2018), 14:38. https://doi.org/10.1007/s11306-018-1334-z

Impaired acylcarnitine profile in transfusion-dependent beta-thalassemia major patients in Bangladesh
Suprovath Kumar Sarker, Md Tarikul Islam, Golam Sarower Bhuyan, Nusrat Sultana, Mst. Noorjahan Begum, Mohammad Al Mahmud-Un-Nabi, Md. Abdulla Al Noman Howladar, Tashmim Farhana Dipta, A.K.M. Muraduzzaman, Syeda Kashfi Qadri, Tahmina Shirin, Salma Sadiya, Manzoor Hussain, Waqar Ahmed Khan, Sharif Akhteruzzaman, Syed Saleheen Qadri, Firdausi Qadri, Kaiissar Mannoor
Journal of Advanced Research (2018), Volume 12, Pages 55-66. https://doi.org/10.1016/j.jare.2018.04.002

Reduced HeLa cell viability in methionine-containing cell culture medium irradiated with microwave-excited atmospheric-pressure plasma
Yohei Takahashi, Yusuke Taki, Keigo Takeda, Hiroshi Hashizume, Hiromasa Tanaka, Kenji Ishikawa, Masaru Hori
Plasma Processes and Polymers (2018), Volume 15, Issue 3. https://doi.org/10.1002/ppap.201700200

The Arabidopsis thaliana Knockout Mutant for Phytochelatin Synthase1 (cad1-3) Is Defective in Callose Deposition, Bacterial Pathogen Defense and Auxin Content, But Shows an Increased Stem Lignification
Maria De Benedictis, Cecilia Brunetti, Elizabeth K. Brauer, Andrea Andreucci, Sorina C. Popescu, Mauro Commisso, Flavia Guzzo, Adriano Sofo, Monica Ruffini Castiglione, Olena K. Vatamaniuk and Luigi Sanità di Toppi
Front. Plant Sci. (2018), Volume 9, Article 19. https://doi.org/10.3389/fpls.2018.00019

Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus-castus
Allison M. Heskes, Tamil C.M. Sundram, Berin A. Boughton, Niels B. Jensen, Nikolaj L. Hansen, Christoph Crocoll, Federico Cozzi, Simon Rasmussen, Britta Hamberger, Björn Hamberger, Dan Staerk, Birger L. Møller, Irini Pateraki
The Plant Journal (2018), Volume 93, Issue 5. https://doi.org/10.1111/tpj.13822

Chemical and Nutritional Characterization of Seed Oil from Cucurbita maxima L. (var. Berrettina) Pumpkin
Domenico Montesano, Francesca Blasi, Maria Stella Simonetti, Antonello Santini, Lina Cossignani
Foods 2018, 7(3), 30. https://doi.org/10.3390/foods7030030

Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion
Yusuke Yamamoto, Kohkichi Hosoda, Taichiro Imahori, Jun Tanaka, Kazuya Matsuo, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Naoko Sato, Takashi Sasayama, Kazuhiro Tanaka, Hiroaki Nagashima, Masaaki Kohta, Eiji Kohmura
Brain Research (2018), Volume 1687, 15, Pages 82-94. https://doi.org/10.1016/j.brainres.2018.03.001

Glycosylceramide modifies the flavor and metabolic characteristics of sake yeast
Jannatul Ferdouse, Yuki Yamamoto, Seiga Taguchi, Yumiko Yoshizaki, Kazunori Takamine, Hiroshi Kitagaki
PeerJ 6:e4768. https://doi.org/10.7717/peerj.4768

Application of adaptive laboratory evolution to overcome a flux limitation in an Escherichia coli production strain
Kento Tokuyama, Yoshihiro Toya, Takaaki Horinouchi, Chikara Furusawa, Fumio Matsuda, Hiroshi Shimizu
Biotechnology and Bioengineering (2018), Volume 115, Issue 6. https://doi.org/10.1002/bit.26568

Fatty Acids and Phytosterols to Discriminate Geographic Origin of Lycium barbarum Berry
L. Cossignani, F. Blasi, M. S. Simonetti, D. Montesano
Food Analytical Methods (2018), Volume 11, Issue 4, pp 1180–1188

Simultaneous detection of multiple inherited metabolic diseases using GC-MS urinary metabolomics by chemometrics multi-class classification strategies
Qin Yang, Lu Xu, Li-Juan Tang, Jiang-Tao Yang, Ben-Qing Wu, Nan Chen, Jian-Hui Jiang, Ru-Qin Yu
Talanta (2018), Volume 186, 15, Pages 489-496. https://doi.org/10.1016/j.talanta.2018.04.081

Nuclear magnetic resonance- and gas chromatography/mass spectrometry-based metabolomic characterization of water-soluble and volatile compound profiles in cabbage vinegar
Satoru Ishihara, Takashi Inaoka, Toshihide Nakamura, Keitarou Kimura, Yasuyo Sekiyama, Satoru Tomita
Journal of Bioscience and Bioengineering (2018), Available online 2. https://doi.org/10.1016/j.jbiosc.2018.02.003

2017

Increased levels of ascorbic acid in the cerebrospinal fluid of cognitively intact elderly patients with major depression: a preliminary study
Kenji Hashimoto, Tamaki Ishima, Yasunori Sato, Davide Bruno, Jay Nierenberg, Charles R. Marmar, Henrik Zetterberg, Kaj Blennow and Nunzio Pomara
Scientific Reportsvolume (2017) 7, Article number: 3485. doi:10.1038/s41598-017-03836-0

Exploration of serum biomarkers for predicting the response to Inchinkoto (ICKT), a Japanese traditional herbal medicine
Masahito Uji, Yukihiro Yokoyama Email author, Katsuya Ohbuchi, Kazuaki Tsuchiya, Chiharu Sadakane, Chika Shimobori, Masahiro Yamamoto, Masato Nagino
Metabolomics (2017) 13:155. DOI 10.1007/s11306-017-1292-x

Novel serum metabolomics‐based approach by gas chromatography/triple quadrupole mass spectrometry for detection of human skin cancers: Candidate biomarkers
Takeshi Fukumoto, Shin Nishiumi, Susumu Fujiwara, Masaru Yoshida, Chikako Nishigori
Journal of Dermatology (2017) 44: 1268–1275. https://doi.org/10.1111/1346-8138.13921

Integrated Transcriptomic and Metabolomic Analysis of Five Panax ginseng Cultivars Reveals the Dynamics of Ginsenoside Biosynthesis
Yun Sun Lee, Hyun-Seung Park, Dong-Kyu Lee, Murukarthick Jayakodi, Nam-Hoon Kim, Hyun Jo Koo, Sang-Choon Lee, Yeon Jeong Kim, Sung Won Kwon and Tae-Jin Yang
Front. Plant Sci. (2017) 19. https://doi.org/10.3389/fpls.2017.01048

Earwax: A neglected body secretion or a step ahead in clinical diagnosis? A pilot study
Engy Shokry, Anselmo Elcana de Oliveira, Melissa Ameloti Gomes Avelino, Mariana Moreira de Deus, Nelson Roberto Antoniosi Filho
Journal of Proteomics (2017) Volume 159, 21, 92-101. https://doi.org/10.1016/j.jprot.2017.03.005

Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer
Yuji Yamashita, Shin Nishiumi, Seishi Kono, Shintaro Takao, Takeshi Azuma and Masaru Yoshida
BMC Cancer (2017) 17:589. https://doi.org/10.1186/s12885-017-3554-4

Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis
Yoshiko Iizuka-Hishikawa, Daisuke Hishikawa, Junko Sasaki, Keiyo Takubo, Motohito Goto, Katsuyuki Nagata, Hiroki Nakanishi, Hideo Shindoua, Tadashi Okamurae, Chizuru Itoi, Kiyotaka Toshimori, Takehiko Sasaki, and Takao Shimizua
The Journal of Biological Chemistry (2017) 292, 12065-12076. doi: 10.1074/jbc.M117.791277

Determination of endogenous inflammation-related lipid mediators in ischemic stroke rats using background subtracting calibration curves by liquid chromatography-tandem mass spectrometry
Yang Yang, Qisheng Zhong, Canlong Mo, Hao Zhang, Ting Zhou Email author, Wen Tan Email author
Analytical and Bioanalytical Chemistry (2017) Volume 409, Issue 28, 6537–6547. https://doi.org/10.1007/s00216-017-0600-7

Prostaglandin D₂ metabolite in urine is an index of food allergy
Shingo Maeda, Tatsuro Nakamura, Hiroaki Harada, Yuri Tachibana, Kosuke Aritake, Tatsuo Shimosawa, Yutaka Yatomi and Takahisa Murata
Scientific Reports (2017) volume 7, Article number: 17687. doi:10.1038/s41598-017-17798-w

Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism
Rosilene Cristina Rossetto Burgos, Johannes Cornelius Schoeman, Lennart Jan van Winden, Kateřina Červinková, Rawi Ramautar, Eduard P. A. Van Wijk, Michal Cifra, Ruud Berger, Thomas Hankemeier and Jan van der Greef
Scientific Reportsvolume (2017) 7, Article number: 1229. doi:10.1038/s41598-017-01229-x

Novel comprehensive multidimensional liquid chromatography approach for elucidation of the microbosphere of shikimate-producing Escherichia coli SP1.1/pKD15.071 strain
Francesco Cacciola, Domenica Mangraviti, Francesca Rigano, Paola Donato, Paola Dugo, Luigi Mondello
Analytical and Bioanalytical Chemistry (2017), 1–10. https://doi.org/10.1007/s00216-017-0744-5

Alpha‐Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction
Karmveer Singh, Linda Krug, Abhijit Basu, Patrick Meyer, Nicolai Treiber, Seppe Vander Beken, Meinhard Wlaschek, Stefan Kochanek, Wilhelm Bloch, Hartmut Geiger, Pallab Maity, Karin Scharffetter‐Kochanek
Stem Cells (2017) Volume 35, Issue 7, 1704-1718. https://doi.org/10.1002/stem.2629

A Systematic Approach to Time-series Metabolite Profiling and RNA-seq Analysis of Chinese Hamster Ovary Cell Culture
Han-Hsiu Hsu, Michihiro Araki, Masao Mochizuki, Yoshimi Hori, Masahiro Murata, Prihardi Kahar, Takanobu Yoshida, Tomohisa Hasunuma and Akihiko Kondo
Scientific Reports volume (2017) 7, Article number: 43518. doi:10.1038/srep43518

Metabolic profiling of Drosophila melanogaster metamorphosis: a new insight into the central metabolic pathways
Phan Nguyen Thuy An, Masamitsu Yamaguchi, Eiichiro Fukusaki
Metabolomics (2017) 13:29. https://doi.org/10.1007/s11306-017-1167-1

Effects of Diet Quality and Psychosocial Stress on the Metabolic Profiles of Mice
Tatsuhiko Goto, Shozo Tomonaga, Atsushi Toyoda
Journal of Proteome Research 2017, 16, 1857−1867 DOI: 10.1021/acs.jproteome.6b00859

Effect of long-distance transportation on serum metabolic profiles of steer calves
Satoshi TAKEMOTO, Shozo TOMONAGA, Masayuki FUNABA, Tohru MATSUI
Animal Science Journal (2017) doi:10.1111/asj.12870

Effects of high ambient temperature on plasma metabolomic profiles in chicks
Shozo TOMONAGA, Hirofumi OKUYAMA, Tetsuya TACHIBANA, Ryosuke MAKINO
Animal Science Journal (2017) doi:10.1111/asj.12951

Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals
Tetsuya Kimura, Shigeyuki Nada, Noriko Takegahara, Tatsusada Okuno, Satoshi Nojima, Sujin Kang, Daisuke Ito, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuichi Mitsui, Natsuki Sakurai, Hana Sarashina-Kida, Masayuki Nishide, Yohei Maeda, Hyota Takamatsu, Daisuke Okuzaki, Masaki Yamada, Masato Okada, and Atsushi Kumanogoh
Nature Communications 2017 February 27; 8: 14711. DOI: 10.1038/ncomms13130

The use of on-line SFE-SFC/MS/MS to analyze disease biomarkers in dried serum spots compared with serum analysis using LC/MS/MS
Makoto Suzuki, Shin Nishiumi, Takashi Kobayashi, Arata Sakai, Yosuke Iwata, Takato Uchikata, Yoshihiro Izumi, Takeshi Azuma, Takeshi Bamba, Masaru Yoshida
Rapid Communications in Mass Spectrometry, Volume 31, Issue 10, Version of Record online: 18 APR 2017

Novel serum metabolomics-based approach by gas chromatography/triple quadrupole mass spectrometry for detection of human skin cancers: candidate biomarkers
Fukumoto T., Nishiumi S., Fujiwara S., Yoshida M., Nishigori C.
The Journal of Dermatology DOI: 10.1111/1346-8138.13921

Evaluation of a novel system for analyzing hydrophilic blood metabolites
Shin Nishiumi, Keisuke Shima, Takeshi Azuma, Masaru Yoshida
Journal of Bioscience and Bioengineering 2017 Jun;123(6):754-759. DOI: 10.1016/j.jbiosc.2017.01.015. Epub 2017 Mar 11.

Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics
Yuichi Hirata, Takashi Kobayashi, Shin Nishiumi, Kodai Yamanaka, Takashi Nakagawa, Seiji Fujigaki, Takao Iemoto, Makoto Kobayashi, Takuji Okusaka, Shoji Nakamori, Masashi Shimahara, Takaaki Ueno, Akihiko Tsuchida, Naohiro Sata, Tatsuya Ioka, Yohichi Yasunami, Tomoo Kosuge, Takash i Kaneda, Takao Kato, Kazuhiro Yagihara, Shigeyuki Fujita, Tesshi Yamada, Kazufumi Honda, Takeshi Azuma, Masaru Yoshida
Clinica Chimica Acta 468 (2017) 98-104

Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry
S Nishiumi, T Kobayashi, S Kawana, Y Unno, T Sakai, K Okamoto, Y Yamada, K Sudo, T Yamaji, Y Saito, Y Kanemitsu, NT Okita, H Saito, S Tsugane, T Azuma, N Ojima, M Yoshida
Oncotarget DOI: 10.18632/oncotarget.15081

Discovery of Metabolite Biomarkers for Acute Ischemic Stroke Progression
Peifang Liu, Ruiting Li, Anton A. Antonov, Lihua Wang, Wei Li, Yunfei Hua, Huimin Guo, Lijuan Wang, Peijia Liu, Lixia Chen, Yuan Tian, Fengguo Xu, Zunjian Zhang, Yulan Zhu, and Yin Huang
J. Proteome Res., Just Accepted Manuscript DOI: 10.1021/acs.jproteome.6b00779

2016

Fluctuations in metabolite content in the liver of magnesium-deficient rats
Mei Shigematsu, Ryosuke Nakagawa, Shozo Tomonaga, Masayuki Funaba, Tohru Matsui
British Journal of Nutrition (2016), 116, 1694–1699 DOI: 10.1017/S0007114516003676

13C-metabolic flux analysis of human adenovirus infection: Implications for viral vector production
Nuno Carinhas, Alexey Koshkin, Daniel A.M. Pais, Paula M. Alves, Ana P. Teixeira
Biotechnology and Bioengineering DOI: 10.1002/bit.26063

Sensory and Flavor Chemistry Characteristics of Australian Beef: Influence of Intramuscular Fat, Feed, and Breed
Damian Frank, Alex Ball, Joanne Hughes, Raju Krishnamurthy, Udayasika Piyasiri, Janet Stark, Peter Watkins, and Robyn Warner
J. Agric. Food Chem., 2016, 64 (21), pp 4299-4311 DOI: 10.1021/acs.jafc.6b00160

Metabolic Profiling in Chinese Cabbage (Brassica rapa L. subsp. pekinensis) Cultivars Reveals that Glucosinolate Content Is Correlated with Carotenoid Content
Seung-A Baek, Young-Ho Jung, Sun-Hyung Lim, Sang Un Park, and Jae Kwang Kim
J. Agric. Food Chem., 2016, 64 (21), pp 4426-4434 DOI: 10.1021/acs.jafc.6b01323
LC-Q-TOF: Bruker

Evaluation of Palm Oil as a Suitable Vegetable Oil for Vitamin A Fortification Programs
Marc Pignitter, Natalie Hernler, Mathias Zaunschirm, Julia Kienesberger, Mark Manuel Somoza, Klaus Kraemer, and Veronika Somoza
Nutrients 2016, 8(6), 378; doi: 10.3390/nu8060378

The development of plasma pseudotargeted GC-MS metabolic profiling and its application in bladder cancer
Yang Zhou, Ruixiang Song, Zhensheng Zhang, Xin Lu, Zhongda Zeng, Chunxiu Hu, Xinyu Liu, Yanli Li, Jianguo Hou, Yinghao Sun, Chuanliang Xu, Guowang Xu
Analytical and Bioanalytical Chemistry September 2016, Volume 408, Issue 24, pp 6741-6749

Metabolic flux profiling of MDCK cells during growth and canine adenovirus vector production
Nuno Carinhas, Daniel A. M. Pais, Alexey Koshkin, Paulo Fernandes, Ana S. Coroadinha, Manuel J. T. Carrondo, Paula M. Alves, and Ana P. Teixeiraa
Sci Rep. 2016; 6: 23529. doi: 10.1038/srep23529

Multiple roles of lactic acid bacteria microflora in the formation of marker flavour compounds in traditional chinese paocai
Nan Zhao, Chuchu Zhang, Qin Yang, Bo Yang, Wenwei Lu, Dongyao Li, Xiaoming Liu, Fengwei Tian, Hao Zhang and Wei Chen
RSC Adv., 2016,6, 89671-89678 DOI: 10.1039/C6RA12474G

Prediction of Periodontal Inflammation via Metabolic Profiling of Saliva
M. Kuboniwa, A. Sakanaka, E. Hashino, T. Bamba, E. Fukusaki, A. Amano
Journal of Dental Research 2016, Vol. 95(12) 1381-1386 DOI: 10.1177/0022034516661142

2-Aminobutyric acid modulates glutathione homeostasis in the myocardium
Yasuhiro Irino, Ryuji Toh, Manabu Nagao, Takeshige Mori, Tomoyuki Honjo, Masakazu Shinohara, Shigeyasu Tsuda, Hideto Nakajima, Seimi Satomi-Kobayashi, Toshiro Shinke, Hidekazu Tanaka, Tatsuro Ishida, Okiko Miyata, and Ken-ichi Hirata
Sci Rep. 2016; 6: 36749.

The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a Cross-Sectional Study to Characterize the Metabolome of Healthy Men and Women
Achim Bub, Anita Kriebel, Dipl oec throph (FH), Claudia Dorr, Susanne Bandt, Manuela Rist, Alexander Roth, Eva Hummel, Sabine Kulling, Ingrid Hoffmann, and Bernhard Watzl,
JMIR Res Protoc. 2016 Jul-Sep; 5(3): e146.

A Simultaneous Metabolic Profiling and Quantitative Multimetabolite Metabolomic Method for Human Plasma Using Gas-Chromatography Tandem Mass Spectrometry
Otto I. Savolainen, Ann-Sofie Sandberg, and Alastair B. Ross
J. Proteome Res., 2016, 15 (1), pp 259-265 DOI: 10.1021/acs.jproteome.5b00790

Herring and chicken/pork meals lead to differences in plasma levels of TCA intermediates and arginine metabolites in overweight and obese men and women
Andrew Vincent, Otto I. Savolainen, Partho Sen, Nils-Gunnar Carlsson, Annette Almgren, Helen Lindqvist, Mads Vendelbo Lind, Ingrid Undeland, Ann-Sofie Sandberg, Alastair B. Ross
Mol. Nutr. Food Res.. doi: 10.1002/mnfr.201600400

Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia
Feng Li, Tomofumi Fushima, Gen Oyanagi, H. W. Davin Townley-Tilson, Emiko Satob, Hironobu Nakada, Yuji Oe, John R. Hagamana, Jennifer Wildera, Manyu Li, Akiyo Sekimoto, Daisuke Saigusa, Hiroshi Sato, Sadayoshi Ito, J. Charles Jennette, Nobuyo Maeda, S. Ananth Karumanchi, Oliver Smithies, and Nobuyuki Takahashi
Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13450-13455.

GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to 13C-metabolic flux analysis of Escherichia coli central metabolism
Nobuyuki Okahashi, Shuichi Kawana, Junko Iida, Hiroshi Shimizu, Fumio Matsuda
Analytical and Bioanalytical Chemistry September 2016, Volume 408, Issue 22, pp 6133-6140

Metabolome analysis reveals the effect of carbon catabolite control on the poly(γ-glutamic acid) biosynthesis of Bacillus licheniformis ATCC 9945
Hitoshi Mitsunaga, Lena Meissner, Thomas Palmen, Takeshi Bamba, Jochen Buchs, Eiichiro Fukusaki
Journal of Bioscience and Bioengineering Volume 121, Issue 4, April 2016, Pages 413-419

Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis
Daiki Setoyama, Takahiro A. Kato, Ryota Hashimoto, Hiroshi Kunugi, Kotaro Hattori, Kohei Hayakawa, Mina Sato-Kasai, Norihiro Shimokawa, Sachie Kaneko, Sumiko Yoshida, Yu-ichi Goto, Yuka Yasuda, Hidenaga Yamamori, Masahiro Ohgidani, Noriaki Sagata, Daisuke Miura, Dongchon Kang, Shigenobu Kanba
PLoS One. 2016 http://dx.doi.org/10.1371/journal.pone.0165267

Anionic metabolite biosynthesis enhanced by potassium under dark, anaerobic conditions in cyanobacteria
Sakiko Ueda, Yuhki Kawamura, Hiroko Iijima, Mitsuharu Nakajima, Tomokazu Shirai, Mami Okamoto, Akihiko Kondo, Masami Yokota Hirai, and Takashi Osanaia
Sci Rep. 2016; 6: 32354. doi: 10.1038/srep32354

LC-MS/MS-based metabolome analysis detected changes in the metabolic profiles of small and large intestinal adenomatous polyps in ApcMin/+ mice
Makoto Suzuki, Shin Nishiumi, Takashi Kobayashi, Takeshi Azuma, Masaru Yoshida
Metabolomics　April 2016, DOI: 10.1007/s11306-016-0988-7

Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer
A Blomme, B Costanza, P de Tullio, M Thiry, G Van Simaeys, S Boutry, G Doumont, E Di Valentin, T Hirano, T Yokobori, S Gofflot, O Peulen, A Bellahcene, F Sherer, C Le Goff, E Cavalier, A Mouithys-Mickalad, F Jouret, P G Cusumano, E Lifrange, R N Muller, S Goldman, P Delvenne, E De Pauw, M Nishiyama, V Castronovo and A Turtoi
Oncogene , (24 October 2016) | doi:10.1038/onc.2016.369

Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis
Junzeng Fu, Johannes C. Schoeman, Amy C. Harms, Herman A. van Wietmarschen, Rob J. Vreeken, Ruud Berger, Bart V. J. Cuppen, Floris P. J. G. Lafeber, Jan van der Greef, Thomas Hankemeier
Analytical and Bioanalytical Chemistry September 2016, Volume 408, Issue 23, pp 6307-6319

Intact Endogenous Metabolite Analysis of Mice Liver by Probe Electrospray Ionization/Triple Quadrupole Tandem Mass Spectrometry and Its Preliminary Application to in Vivo Real-Time Analysis
Kei Zaitsu, Yumi Hayashi, Tasuku Murata, Tomomi Ohara, Kenta Nakagiri, Maiko Kusano, Hiroki Nakajima, Tamie Nakajima, Tetsuya Ishikawa, Hitoshi Tsuchihashi, and Akira Ishii
DOI: 10.1021/acs.analchem.5b04046

Modulation of the cellular content of metabolites in adipocytes by insulin
Qiao Y, Tomonaga S, Matsui T, Funaba M.
Mol Cell Endocrinol. 2016 Jan 23. pii: S0303-7207(16)30017-X. doi: 10.1016/j.mce.2016.01.017.

A Novel Strategy for Large-Scale Metabolomics Study by Calibrating Gross and Systematic Errors in Gas Chromatography Mass Spectrometry
Yanni Zhao, Zhiqiang Hao, Chunxia Zhao, Jieyu Zhao, Junjie Zhang, Yanli Li, Lili Li, Xin Huang, Xiaohui Lin, Zhongda Zeng, Xin Lu, and Guowang Xu
Analytical chemistry 2016 (in press)

Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production
Shingo Noguchi, Sastia P Putri, Ethan I Lan, Walter A Lavina, Yudai Dempo, Takeshi Bamba, James C Liao, Eiichiro
Fukusaki Original Article Metabolomics February 2016, 12:26

 

2015

Investigating oxalate biosynthesis in the wooddecaying fungus Gloeophyllum trabeum using 13C metabolic flux analysis
Liangpeng Zhuang, Weihua Guo, Makoto Yoshida,c Xueyang Feng and Barry Goodell
RSC Advances RSC Adv., 2015,5, 104043-104047 DOI: 10.1039/C5RA19203J

Profiling of plasma metabolites in canine oral melanoma using gas chromatography-mass spectrometry
Kawabe M, Baba Y, Tamai R, Yamamoto R, Komori M, Mori T, Takenaka S
J Vet Med Sci. 2015 Aug;77(8):1025-8. doi: 10.1292/jvms.14-0641.

Nano-scale liquid chromatography coupled to tandem mass spectrometry using the multiple reaction monitoring mode based quantitative platform for analyzing multiple enzymes associated with central metabolic pathways of Saccharomyces cerevisiae using ultra fast mass spectrometry
Fumio Matsuda, Tairo Ogura, Atsumi Tomita, Ichiro Hirano, Hiroshi Shimizu
J Biosci Bioeng. 2015 Jan;119(1):117-20. doi: 10.1016/j.jbiosc.2014.06.010.

Rikkunshito Ameliorates Cancer Cachexia Partly through Elevation of Glucarate in Plasma.
Ohbuchi K, Nishiumi S, Fujitsuka N, Hattori T, Yamamoto M, Inui A, Azuma T, Yoshida M
Evid Based Complement Alternat Med. 2015;2015:871832. doi: 10.1155/2015/871832.

Multi-Component Profiling of Trace Volatiles in Blood by Gas Chromatography/Mass Spectrometry with Dynamic Headspace Extraction
Shoji Kakuta, Toshiyuki Yamashita, Shin Nishiumi, Masaru Yoshida, Eiichiro Fukusaki, and Takeshi Bamba
Mass Spectrometry Vol.4 (2015) No.1 p.A0034

Metabolome disruption of the rat cerebrum induced by the acute toxic effects of the synthetic cannabinoid MAM-2201
Kei Zaitsu, Yumi Hayashi, Kei Suzuki, Hiroshi Nakayama, Nanpei Hattori, Rina Takahara, Maiko Kusano, Hitoshi Tsuchihashi, Akira Ishii
Life Sciences 137 (2015) 49-55

Application of gas chromatography/flame ionization detector-based metabolite fingerprinting for authentication of Asian palm civet coffee (Kopi Luwak)
Udi Jumhawan, Sastia Prama Putri, Yusianto,Takeshi Bamba, and Eiichiro Fukusaki
Arch Biochem Biophys. 2010 Dec 15;504(2):221-7. doi: 10.1016/j.abb.2010.09.001.

A preliminary study on postmortem interval estimation of suffocated rats by GC-MS/MS-based plasma metabolic profiling
Takako Sato, Kei Zaitsu, Kento Tsuboi, Masakatsu Nomura, Maiko Kusano, Noriaki Shima, Shuntaro Abe , Akira Ishii, Hitoshi Tsuchihashi, Koichi Suzuki
Anal Bioanal Chem DOI 10.1007/s00216-015-8584-7.
 

2014

High-sensitivity detection of short-chain fatty acids in porcine ileal, cecal, portal and abdominal blood by gas chromatography-mass spectrometry
Takamitsu TSUKAHARA, Noriko MATSUKAWA, Shozo TOMONAGA, Ryo INOUE, Kazunari USHIDA and Kuniyasu OCHIAI
Animal Science Journal (2014) 85, 494-498

Profiling of Serum Metabolites in Canine Lymphoma Using Gas Chromatography Mass Spectrometry
Reo TAMAI, Masaru FURUYA, Shingo HATOYA, Hideo AKIYOSHI, Ryohei YAMAMOTO,Yoshiaki KOMORI, Shin-ichi YOKOI, Kenichiro TANI, Yuji HIRANO, Masayuki KOMORI and Shigeo TAKENAKA
J. Vet. Med. Sci. 76(11): 1513-1518, 2014

A novel gas chromatography mass spectrometry-based serum diagnostic and assessment approach to ulcerative colitis.
Kohashi M, Nishiumi S, Ooi M, Yoshie T, Matsubara A, Suzuki M, Hoshi N, Kamikozuru K, Yokoyama Y, Fukunaga K, Nakamura S, Azuma T, Yoshida M.
J. Crohns Colitis. 2014 Sep;8(9):1010-21. doi: 10.1016/j.crohns.2014.01.024.

Supercritical fluid extraction as a preparation method for mass spectrometry of dried blood spots.
Matsubara A, Izumi Y, Nishiumi S, Suzuki M, Azuma T, Fukusaki E, Bamba T, Yoshida M
J. Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 15;969:199-204. doi: 10.1016/j.jchromb.2014.08.013.

Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
Zaitsu K, Miyawaki I, Bando K, Horie H, Shima N, Katagi M, Tatsuno M, Bamba T, Sato T, Ishii A, Tsuchihashi H, Suzuki K, Fukusaki E
Anal Bioanal Chem. 2014 Feb;406(5):1339-54. doi: 10.1007/s00216-013-7234-1.

Metabolic Profiling of Retrograde Pathway Transcription Factors Rtg1 and RtgM3 Knockout Yeast
Zanariah Hashim, Yukio Mukai, Takeshi Bamba and Eiichiro Fukusaki
Metabolites 2014, 4, 580-598; doi:10.3390/metabo4030580.

Analysis of the correlation between dipeptides and taste differences among soy sauces by using metabolomics-based component profiling
Shinya Yamamoto, Kazuki Shiga, Yukako Kodama,Miho Imamura, Riichiro Uchida, Akio Obata, Takeshi Bamba, and Eiichiro Fukusaki
Journal of Bioscience and Bioengineering VOL. 118 No. 1, 56e63, 2014

Gas chromatography/mass spectrometry based component profiling and quality prediction for Japanese sake
Natsuki Mimura, Atsuko Isogai, Kazuhiro Iwashita,Takeshi Bamba, and Eiichiro Fukusaki
Journal of Bioscience and Bioengineering VOL. 118 No. 4, 406e414, 2014

Novel Strategy for Non-Targeted Isotope-Assisted Metabolomics by Means of Metabolic Turnover and Multivariate Analysis
Yasumune Nakayama, Yoshihiro Tamada, Hiroshi Tsugawa, Takeshi Bamba and Eiichiro Fukusaki
Metabolites 2014, 4, 722-739; doi:10.3390/metabo4030722.
 

2013

Gas Chromatography-Mass Spectrometry-Based Metabolic Profiling of Cerebrospinal Fluid from Epileptic Dogs
Tetsuya HASEGAWA, Maho SUMITA, Yusuke HORITANI, Reo TAMAI, Katsuhiro TANAKA, Masayuki KOMORI and Shigeo TAKENAKA
J. Vet Med Sci. 2014 Apr;76(4):517-22. Epub 2013 Dec 13.

Metabolomic investigation of pathogenesis of myxosporean emaciation disease of tiger puffer fish Takifugu rubripes
H Kodama, K Otani, T Iwasaki, S Takenaka, Y Horitani and H Togase
Journal of Fish Diseases 2013

A novel serum metabolomics-based diagnostic approach to pancreatic cancer
Kobayashi T, Nishiumi S, Ikeda A, Yoshie T, Sakai A, Matsubara A, Izumi Y, Tsumura H, Tsuda M, Nishisaki H, Hayashi N, Kawano S, Fujiwara Y, Minami H, Takenawa T, Azuma T, Yoshida M
Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):571-9. doi: 10.1158/1055-9965.EPI-12-1033.

Monitoring the ripening process of Cheddar cheese based on hydrophilic component profiling using gas chromatography-mass spectrometry
H. Ochi , Y. Sakai , H. Koishihara , F. Abe , T. Bamba , and E. Fukusaki
J. Dairy Sci. 96 :7427-7441

Selection of Discriminant Markers for Authentication of Asian Palm Civet Coffee (Kopi Luwak): A Metabolomics Approach
Udi Jumhawan, Sastia Prama Putri, Yusianto, Erly Marwani, Takeshi Bamba, and Eiichiro Fukusaki
J. Agric. Food Chem. 2013, 61, 7994-8001
 

2012

A novel serum metabolomics-based diagnostic approach for colorectal cancer
Nishiumi S, Kobayashi T, Ikeda A, Yoshie T, Kibi M, Izumi Y, Okuno T, Hayashi N, Kawano S, Takenawa T, Azuma T, Yoshida M
PLoS One. 2012;7(7):e40459. doi: 10.1371/journal.pone.0040459.
 

2011

GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium
Shiomi Y, Nishiumi S, Ooi M, Hatano N, Shinohara M, Yoshie T, Kondo Y, Furumatsu K, Shiomi H, Kutsumi H, Azuma T, Yoshida M
Inflamm Bowel Dis. 2011 Nov;17(11):2261-74. doi: 10.1002/ibd.21616.

GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis
Ooi M, Nishiumi S, Yoshie T, Shiomi Y, Kohashi M, Fukunaga K, Nakamura S, Matsumoto T, Hatano N, Shinohara M, Irino Y, Takenawa T, Azuma T, Yoshida M
Inflamm Res. 2011 Sep;60(9):831-40. doi: 10.1007/s00011-011-0340-7.
 

2010

Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport
Kawano Y, Nishiumi S, Tanaka S, Nobutani K, Miki A, Yano Y, Seo Y, Kutsumi H, Ashida H, Azuma T, Yoshida M
Arch Biochem Biophys. 2010 Dec 15;504(2):221-7. doi: 10.1016/j.abb.2010.09.001.